Публикации
за предотвратяване разпространението на SARS-CoV2 и на други патогени
Проект в областта на медико-биологични проблеми, с финансиране за фундаментални научни изследвания по обществени предизвикателства, свързани с пандемията от COVID-19 – 2020 г.

2023
Georgieva, Stela; Todorov, Petar; Staneva, Desislava; Grozdanov, Petar; Nikolova, Ivanka; Grabchev, Ivo
Metal-peptide complexes with antimicrobial potential for cotton fibres protection. Journal Article
In: Journal of Functional Biomaterials, vol. 14(2), iss. 106, 2023.
Abstract | Links | BibTeX | Етикети:
@article{nokey,
title = {Metal-peptide complexes with antimicrobial potential for cotton fibres protection.},
author = {Stela Georgieva and Petar Todorov and Desislava Staneva and Petar Grozdanov and Ivanka Nikolova and Ivo Grabchev},
url = {http://antiviraltextile.eu/wp-content/uploads/2023/03/jfb-14-00106.pdf
https://www.mdpi.com/2079-4983/14/2/106},
doi = {https://doi.org/10.3390/jfb14020106},
year = {2023},
date = {2023-02-14},
journal = {Journal of Functional Biomaterials},
volume = {14(2)},
issue = {106},
abstract = {A study of the formation of copper (II) complexes with hemorphin peptide motifs in alkalic
water solutions is presented. The effect of the peptide ligand on the complexing properties of the Cu
(II) ion was quantified by giving the stoichiometry and stability of the complex compounds in the
medium in which they are formed using voltammetric (cyclic) and spectral (UV-Vis and fluorimetric)
analytical techniques. The resulting complexes were examined via IR spectroscopy to detect M-N
and M-O oscillations and using the EPR approach in solution and in the solid phase to view the
coordination and ligand binding regime. The possibility of the synergistic action of copper ions
in the antivirus protection processes of cotton fibers coated in the same solvent with the newly
obtained complex compounds was also investigated. One of the advantages is the formation of the
complexes in an environment where the immobilization takes place, which contributes to increasing
the efficiency of the process. The obtained results may serve as an aid for future more detailed
biological studies of structure–activity relationships (SARs).
Keywords: peptide; hemorphin; copper–peptide complexes; Cu(II) ions; cotton; antivirus protection},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
water solutions is presented. The effect of the peptide ligand on the complexing properties of the Cu
(II) ion was quantified by giving the stoichiometry and stability of the complex compounds in the
medium in which they are formed using voltammetric (cyclic) and spectral (UV-Vis and fluorimetric)
analytical techniques. The resulting complexes were examined via IR spectroscopy to detect M-N
and M-O oscillations and using the EPR approach in solution and in the solid phase to view the
coordination and ligand binding regime. The possibility of the synergistic action of copper ions
in the antivirus protection processes of cotton fibers coated in the same solvent with the newly
obtained complex compounds was also investigated. One of the advantages is the formation of the
complexes in an environment where the immobilization takes place, which contributes to increasing
the efficiency of the process. The obtained results may serve as an aid for future more detailed
biological studies of structure–activity relationships (SARs).
Keywords: peptide; hemorphin; copper–peptide complexes; Cu(II) ions; cotton; antivirus protection
Georgieva, Stela; Todorov, Petar; Staneva, Desislava; Grozdanov, Petar; Nikolova, Ivanka; Grabchev, Ivo
Metal-peptide complexes with antimicrobial potential for cotton fibres protection. Journal Article
In: Journal of Functional Biomaterials, vol. 14, iss. 2, 2023.
BibTeX | Етикети:
@article{nokey,
title = {Metal-peptide complexes with antimicrobial potential for cotton fibres protection. },
author = {Stela Georgieva and Petar Todorov and Desislava Staneva and Petar Grozdanov and Ivanka Nikolova and Ivo Grabchev},
editor = {Dana Maria Copolovici and Robert Vasile Gradinaru},
year = {2023},
date = {2023-02-14},
journal = {Journal of Functional Biomaterials},
volume = {14},
issue = {2},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
2022
Todorov, Petar; Georgieva, Stela; Tchekalarova, Jana
In: vol. 2022, 15, iss. 1425, 2022.
Abstract | Links | BibTeX | Етикети:
@article{nokey,
title = {Recent synthesis, characterization and pharmacological evaluation of multifunctional hemorphins containing non-natural amino acids with potential biological importance.},
author = {Petar Todorov and Stela Georgieva and Jana Tchekalarova},
editor = {Adriano Mollica},
url = {http://antiviraltextile.eu/wp-content/uploads/2023/03/pharmaceuticals-15-01425-v2.pdf
https://www.mdpi.com/1424-8247/15/11/1425 },
doi = {https://doi.org/10.3390/ ph15111425},
year = {2022},
date = {2022-11-17},
volume = {2022, 15},
issue = {1425},
abstract = {Abstract: The endogenous hemorphins are bioactive peptides with activity on opioid receptors. They
are extensively studied and summarized in numerous reviews. During the last decade, several
research teams have synthesized, characterized, and pharmacologically evaluated synthetic hemorphin
analogs containing unusual amino acids, D-amino acids, -aminophosphonic acids, and their
derivatives. The present review summarizes the current studies on short-chain synthetic hemorphin
peptide derivates containing non-natural amino acids. This review focuses on the structure–activity
relationship analysis, details on specific methods for their characterization, and the advantage of synthetic
hemorphin analogs compared to endogenous peptides as potent biologically active compounds
with a complex mechanism of action.
Keywords: hemorphins; non-natural amino acids; unusual amino acids; non-proteinogenic amino
acids; biological activity; electrochemical behavior of peptides},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
are extensively studied and summarized in numerous reviews. During the last decade, several
research teams have synthesized, characterized, and pharmacologically evaluated synthetic hemorphin
analogs containing unusual amino acids, D-amino acids, -aminophosphonic acids, and their
derivatives. The present review summarizes the current studies on short-chain synthetic hemorphin
peptide derivates containing non-natural amino acids. This review focuses on the structure–activity
relationship analysis, details on specific methods for their characterization, and the advantage of synthetic
hemorphin analogs compared to endogenous peptides as potent biologically active compounds
with a complex mechanism of action.
Keywords: hemorphins; non-natural amino acids; unusual amino acids; non-proteinogenic amino
acids; biological activity; electrochemical behavior of peptides
Zheleva, D.; Koleva, M.; Stoikova, D.; Grabcheva, D.; Todorov, P.
Methods for Modification of Cotton Fabrics with Gelatin – Glutaraldehyde and ZnO nanoparticles. Conference
9th International Conference on Advanced Materials and System, ICAMS 2022 – 9th International Conference on Advanced Materials and Systems, 2022.
Abstract | Links | BibTeX | Етикети:
@conference{nokey,
title = {Methods for Modification of Cotton Fabrics with Gelatin – Glutaraldehyde and ZnO nanoparticles.},
author = {D. Zheleva and M. Koleva and D. Stoikova and D. Grabcheva and P. Todorov},
url = {http://antiviraltextile.eu/wp-content/uploads/2023/03/II_biomaterials_biotechnologies_29.pdf},
doi = {https://doi.org/10.24264/icams-2022.II.29},
year = {2022},
date = {2022-10-28},
booktitle = {9th International Conference on Advanced Materials and System},
pages = {253-258},
publisher = {ICAMS 2022 – 9th International Conference on Advanced Materials and Systems},
abstract = {Cotton fabrics have good water absorption properties, air permeability, non-toxicity, but
microorganisms easily damage them. Collagen is a commonly used biomaterial that has properties
such as biocompatibility, biodegradability, non-toxicity, but with poor mechanical properties.
Glutaraldehyde is the main cross-linking agent for collagen and characterized by antimicrobial
properties. ZnO nanoparticles exhibiting antibacterial, antifungal, anticorrosive and protective
properties against UV, is widely applicable in medicine. The combination of all these components
in one biocomposite with potential antimicrobial properties and healing effect can find application
in medical practice. In this study, an attempt was made to improve the properties of cotton fabric
by impregnating it with gelatin hydrogel cross-linked with glutaraldehyde and containing ZnO
nanoparticles. Three methods of modification were applied, varying the mixing regimes of the
components and the conditions. The composite materials were investigated by means of SEM,
FTIR, and fluorescence analysis. The morphological analyzes of the samples modified by different
methods show that the spherical particles of ZnO have changed into a flower-like structures; the
particles are covered by the collagen film; and dispersed and agglomerated in certain places. FTIR
analyzes prove interactions between the organic and inorganic components. This is also confirmed
by the observed fluorescent properties, which are of different intensity. All these observations
suggest good antibacterial properties that will be the subject of future research.
Keywords: biocomposites, cotton, gelatin, ZnO nanoparticles},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
microorganisms easily damage them. Collagen is a commonly used biomaterial that has properties
such as biocompatibility, biodegradability, non-toxicity, but with poor mechanical properties.
Glutaraldehyde is the main cross-linking agent for collagen and characterized by antimicrobial
properties. ZnO nanoparticles exhibiting antibacterial, antifungal, anticorrosive and protective
properties against UV, is widely applicable in medicine. The combination of all these components
in one biocomposite with potential antimicrobial properties and healing effect can find application
in medical practice. In this study, an attempt was made to improve the properties of cotton fabric
by impregnating it with gelatin hydrogel cross-linked with glutaraldehyde and containing ZnO
nanoparticles. Three methods of modification were applied, varying the mixing regimes of the
components and the conditions. The composite materials were investigated by means of SEM,
FTIR, and fluorescence analysis. The morphological analyzes of the samples modified by different
methods show that the spherical particles of ZnO have changed into a flower-like structures; the
particles are covered by the collagen film; and dispersed and agglomerated in certain places. FTIR
analyzes prove interactions between the organic and inorganic components. This is also confirmed
by the observed fluorescent properties, which are of different intensity. All these observations
suggest good antibacterial properties that will be the subject of future research.
Keywords: biocomposites, cotton, gelatin, ZnO nanoparticles
Todorov, Petar; Georgieva, Stela; Peneva, Petia; Staneva, Desislava; Grabchev, Ivo
Synthesis, characterization and antiviral properties of novel functionalized textile materials with fluorescent N-modified bioactive peptides with 1,8-naphthalimides and their Cu(II)/ Zn(II) complexes Presentation Forthcoming
XXVll EFMC International Symposium on Medicinal Chemistry, Nice, France , 08.09.2022.
@misc{nokey,
title = {Synthesis, characterization and antiviral properties of novel functionalized textile materials with fluorescent N-modified bioactive peptides with 1,8-naphthalimides and their Cu(II)/ Zn(II) complexes},
author = {Petar Todorov and Stela Georgieva and Petia Peneva and Desislava Staneva and Ivo Grabchev},
url = {https://www.efmc-ismc.org/programme},
year = {2022},
date = {2022-09-08},
howpublished = {XXVll EFMC International Symposium on Medicinal Chemistry, Nice, France },
keywords = {},
pubstate = {forthcoming},
tppubtype = {presentation}
}
Peneva, Petia; Georgieva, Stela; Todorov, Petar; Staneva, Desislava; Grabchev, Ivo
Functionalized textile materials with fluorescent dendrimers containing bioactive peptides and their Cu(II)/ Zn(II) complexes with antimicrobial properties Presentation Forthcoming
XXVll EFMC International Symposium on Medicinal Chemistry, Nice, France, 08.09.2022.
@misc{nokey,
title = {Functionalized textile materials with fluorescent dendrimers containing bioactive peptides and their Cu(II)/ Zn(II) complexes with antimicrobial properties},
author = {Petia Peneva and Stela Georgieva and Petar Todorov and Desislava Staneva and Ivo Grabchev},
url = {https://www.efmc-ismc.org/programme},
year = {2022},
date = {2022-09-08},
howpublished = {XXVll EFMC International Symposium on Medicinal Chemistry, Nice, France},
keywords = {},
pubstate = {forthcoming},
tppubtype = {presentation}
}
Todorov, Petar; Georgieva, Stela; Peneva, Petia; Staneva, Desislava; Grabchev, Ivo
36th European and 12th International Peptide Symposium, Sitges (Barcelona), Spain, 01.09.2022.
@misc{nokey,
title = {Synthesis and characterization of new Rhodamine B-conjugated Hemorphin‐4 analogues for antiviral protection of textile materials},
author = {Petar Todorov and Stela Georgieva and Petia Peneva and Desislava Staneva and Ivo Grabchev},
url = {https://www.eps2022.com/welcome/},
year = {2022},
date = {2022-09-01},
howpublished = {36th European and 12th International Peptide Symposium, Sitges (Barcelona), Spain},
keywords = {},
pubstate = {published},
tppubtype = {presentation}
}

Todorov, P.; Georgieva, S.; Staneva, D.; Peneva, P.; Grozdanov, P.; Nikolova, I.; Vasileva-Tonkova, E.; Grabchev, I.
Study of Novel Peptides for Antimicrobial Protection in Solution and on Cotton Fabric Journal Article
In: Molecules 2022, vol. 27(15), no. 4770, 2022, ISSN: 1420-3049.
Abstract | Links | BibTeX | Етикети:
@article{nokey,
title = {Study of Novel Peptides for Antimicrobial Protection in Solution and on Cotton Fabric},
author = {Todorov, P. and Georgieva, S. and Staneva, D. and Peneva, P. and Grozdanov, P. and Nikolova, I. and Vasileva-Tonkova, E. and Grabchev, I. },
editor = {Hiroyuki Konno and Kenichi Akaji},
doi = {https://doi.org/10.3390/molecules27154770},
issn = {1420-3049},
year = {2022},
date = {2022-07-26},
journal = {Molecules 2022},
volume = {27(15)},
number = {4770},
abstract = {Some new N- and C-modified biomolecular peptide analogues of both VV-hemorphin-5 and VV-hemorphin-7 with varied amino acids (Cys, Glu, His), 1-adamantanecarboxylic acid, and niacin (nicotinic acid) were synthesized by solid-phase peptide synthesis—Fmoc (9-fluorenylmethoxy-carbonyl) chemistry and were characterized in water solutions with different pH using spectroscopic and electrochemical techniques. Basic physicochemical properties related to the elucidation of the peptide structure at physiological pH have been also studied. The results showed that the interaction of peptide compounds with light and electricity preserves the structural and conformational integrity of the compounds in the solutions. Moreover, textile cotton fibers were modified with the new compounds and the binding of the peptides to the surface of the material was proved by FTIR and SEM analysis. Washing the material with an alkaline soap solution did not show a violation of the modified structure of the cotton. Antiviral activity against the human respiratory syncytial virus (HRSV-S2) and human adenovirus serotype 5 (HAdV-5), the antimicrobial activity against B. cereus and P. aeruginosa used as model bacterial strains and cytotoxic effect of the peptide derivatives and modified cotton textile material has been evaluated. Antimicrobial tests showed promising activity of the newly synthesized compounds against the used Gram-positive and Gram-negative bacteria. The compounds C-V, H-V, AC-V, and AH-V were found slightly more active than NH7C and NCH7. The activity has been retained after the deposition of the compounds on cotton fibers. View Full-Text
Keywords: antimicrobial peptides; hemorphins; cotton fabric; absorption; emission; antiviral activity},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Keywords: antimicrobial peptides; hemorphins; cotton fabric; absorption; emission; antiviral activity
Todorov, Petar; Georgieva, Stela; Peneva, Petia; Staneva, Desislava; Grabchev, Ivo
Novel antimicrobial peptides and their complexes for protection of textile materials: Synthesis and characterization Presentation
22nd Tetrahedron Symposium 2022, Lisbon, Portugal, 01.07.2022.
@misc{nokey,
title = {Novel antimicrobial peptides and their complexes for protection of textile materials: Synthesis and characterization},
author = {Petar Todorov and Stela Georgieva and Petia Peneva and Desislava Staneva and Ivo Grabchev},
url = {https://www.elsevier.com/events/conferences/tetrahedron-symposium/programme},
year = {2022},
date = {2022-07-01},
howpublished = {22nd Tetrahedron Symposium 2022, Lisbon, Portugal},
keywords = {},
pubstate = {published},
tppubtype = {presentation}
}

Todorov, P.; Georgieva, S.; Staneva, D.; Peneva, P.; Atanasova, D.; Grabchev, I.
XIX Научна постерна сесия за млади учени, докторанти и студенти - ХТМУ – София, vol. VII-13, UCTM ХТМУ – София, 2022.
@conference{nokey,
title = {Application of metallopeptides and metallodendrimers for textile modification to prevent the spread of viruses and other pathogens},
author = {P. Todorov and S. Georgieva and D. Staneva and P. Peneva and D. Atanasova and I. Grabchev},
url = {http://antiviraltextile.eu/wp-content/uploads/2022/08/XIX_Poster_Session_BookOfAbstracts_17.06.2022.pdf},
year = {2022},
date = {2022-06-17},
booktitle = {XIX Научна постерна сесия за млади учени, докторанти и студенти - ХТМУ – София},
volume = {VII-13},
pages = {110},
publisher = {ХТМУ – София},
organization = {UCTM},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}

Николов, С.; Георгиева, С.; Тодоров, П.; Пенева, П.; Станева, Д.
Антимикробни пептиди като лиганди за образуване на Cu(II) комплекси за защита на памучни тъкани Conference
XIX Научна постерна сесия за млади учени, докторанти и студенти - ХТМУ – София, vol. VII-7, UCTM ХТМУ – София, 2022.
@conference{nokey,
title = {Антимикробни пептиди като лиганди за образуване на Cu(II) комплекси за защита на памучни тъкани},
author = {С. Николов and С. Георгиева and П. Тодоров and П. Пенева and Д. Станева},
url = {http://antiviraltextile.eu/wp-content/uploads/2022/08/XIX_Poster_Session_BookOfAbstracts_17.06.2022.pdf},
year = {2022},
date = {2022-06-17},
booktitle = {XIX Научна постерна сесия за млади учени, докторанти и студенти - ХТМУ – София},
volume = {VII-7},
pages = {104},
publisher = {ХТМУ – София},
organization = {UCTM},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
2021

Todorov, Petar; Georgieva, Stela; Staneva, Desislava; Peneva, Petia; Grozdanov, Petar; Nikolova, Ivanka; Grabchev, Ivo
Synthesis of New Modified with Rhodamine B Peptides for Antiviral Protection of Textile Materials Journal Article
In: Molecules, vol. 26(21), no. 6608, 2021.
Abstract | Links | BibTeX | Етикети:
@article{nokey,
title = {Synthesis of New Modified with Rhodamine B Peptides for Antiviral Protection of Textile Materials},
author = {Petar Todorov and Stela Georgieva and Desislava Staneva and Petia Peneva and Petar Grozdanov and Ivanka Nikolova and Ivo Grabchev},
editor = {Hiroyuki Konno, Kenichi Akaji},
url = {https://www.researchgate.net/publication/355796067_Synthesis_of_New_Modified_with_Rhodamine_B_Peptides_for_Antiviral_Protection_of_Textile_Materials},
doi = {10.3390/molecules26216608},
year = {2021},
date = {2021-10-31},
urldate = {2021-10-31},
journal = {Molecules},
volume = {26(21)},
number = {6608},
abstract = {Here we report on the synthesis and characterization of three new N-modified analogues of hemorphin-4 with rhodamine B. Modified with chloroacetyl, chloride cotton fabric has been dyed and color coordinates of the obtained textile materials were determined. Antiviral and virucidal activities of both the peptide-rhodamine B compounds and the dyed textile material were studied. Basic physicochemical properties (acid-base behavior, solvent influence, kinetics) related to the elucidation of structural activity of the new modified peptides based on their steric open/closed ring effect were studied. The obtained results lead to the conclusion that in protic solvent with change in pH of the environment, direct control over the dyeing of textiles can be achieved. Both the new hybrid peptide compounds and the modification of functionalized textile materials with these bioactive hemorphins showed virucidal activity against the human respiratory syncytial virus (HRSV-S2) and human adenovirus serotype 5 (HAdV-5) for different time intervals (30 and 60 min) and the most active compound was Rh-3},
keywords = {},
pubstate = {published},
tppubtype = {article}
}

Todorov, P.; Staneva, D.; Georgieva, S.; Peneva, P.; Grabchev, I.
9-та Международна конференция по пептиди, Велинград, BULGARIAN PEPTIDE SOCIETY 2021.
Abstract | Links | BibTeX | Етикети:
@conference{nokey,
title = {Synthesis and characterization of new antimicrobial fluorescent peptides for antivirus protection of textile materials},
author = {P. Todorov and D. Staneva and S. Georgieva and P. Peneva and I. Grabchev},
url = {http://antiviraltextile.eu/wp-content/uploads/2022/08/Abstract-Book-Velingrad-27-29-2021-1.pdf},
year = {2021},
date = {2021-08-29},
booktitle = {9-та Международна конференция по пептиди, Велинград},
pages = {43},
organization = {BULGARIAN PEPTIDE SOCIETY},
abstract = {Herein we report on synthesis and characterization of new antimicrobial peptides,
containing fluorophore moiety. The antiviral and virucidal activity have been also discussed. The
newly synthesized compounds have potential for antivirus protection of textile materials against
human respiratory syncytial virus (HRSV-S2). Peptides with antiviral activity against influenza
present the new generation of antiviral drugs with broad-spectrum activity. The great advantage of
peptides against viruses and other pathogens consists in the reduced possibility of developing
resistance during the treatment. Different methods of textile materials functionalization exist in
order to achieve biologically-active effects. The development of a new method has to fulfill the
requirements for a safety to human health, and environment. Therefore, the increasing tendency of
research is seen where the functionalization is performed by the use of non-toxic, biodegradable,
and environmentally-friendly reagents. That's why the aim of this study was to synthesize new
fluorescent peptides as potential antivirus protection of textile materials. In order to elucidate the
influence of fluorophore moiety, we introduced it to the N-side of hemorphin biopeptides. Herein,
the solid-phase synthesis and characterization of new peptides for textile dyeing has been
presented. The crude antimicrobial peptides were purified on an RP-HPLC and the molecular
weights were determined, using ESI-MS, and also determining of the specific angles of optical
rotation. By using combined experimental approaches the structural-textile application has been
investigated by UV-Vis and fluorimetric methods.
Acknowledgments: This work was financial supported by the Bulgarian National Scientific
Fund project КП-06-ДК1/11 of the Ministry of Education and Science, Bulgaria.},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}
containing fluorophore moiety. The antiviral and virucidal activity have been also discussed. The
newly synthesized compounds have potential for antivirus protection of textile materials against
human respiratory syncytial virus (HRSV-S2). Peptides with antiviral activity against influenza
present the new generation of antiviral drugs with broad-spectrum activity. The great advantage of
peptides against viruses and other pathogens consists in the reduced possibility of developing
resistance during the treatment. Different methods of textile materials functionalization exist in
order to achieve biologically-active effects. The development of a new method has to fulfill the
requirements for a safety to human health, and environment. Therefore, the increasing tendency of
research is seen where the functionalization is performed by the use of non-toxic, biodegradable,
and environmentally-friendly reagents. That's why the aim of this study was to synthesize new
fluorescent peptides as potential antivirus protection of textile materials. In order to elucidate the
influence of fluorophore moiety, we introduced it to the N-side of hemorphin biopeptides. Herein,
the solid-phase synthesis and characterization of new peptides for textile dyeing has been
presented. The crude antimicrobial peptides were purified on an RP-HPLC and the molecular
weights were determined, using ESI-MS, and also determining of the specific angles of optical
rotation. By using combined experimental approaches the structural-textile application has been
investigated by UV-Vis and fluorimetric methods.
Acknowledgments: This work was financial supported by the Bulgarian National Scientific
Fund project КП-06-ДК1/11 of the Ministry of Education and Science, Bulgaria.

Todorov, P.; Georgieva, S.; Staneva, D.; Peneva, P.; Atanasova, D.; Grabchev, I.
XVIII Научна постерна сесия за млади учени, докторанти и студенти - ХТМУ – София, vol. VII-11, ХТМУ – София, 2021.
@conference{nokey,
title = {Synthesis and characterization of new rhodamine peptide analogues as potential antivirus protection of textile materials},
author = {P. Todorov and S. Georgieva and D. Staneva and P. Peneva and D. Atanasova and I. Grabchev},
url = {http://antiviraltextile.eu/wp-content/uploads/2022/08/XVIII_Poster_Session_BookOfAbstracts_2021-1.pdf},
year = {2021},
date = {2021-06-25},
booktitle = {XVIII Научна постерна сесия за млади учени, докторанти и студенти - ХТМУ – София},
volume = {VII-11},
pages = {125},
publisher = {ХТМУ – София},
keywords = {},
pubstate = {published},
tppubtype = {conference}
}